Technical glossary
Explore the terminology that underpins bioanalytical workflows, instrumentation, and regulated documentation.
Technical glossary
Explore the terminology that underpins bioanalytical workflows, instrumentation, and regulated documentation.
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ISO 14644
ISO 14644 is the international standard family for cleanrooms and controlled environments. Its core part, ISO 14644-1, classifies air cleanliness by counting ai...
Coalescence
Coalescence is the physical process by which two or more droplets, bubbles, or particles merge to form a single larger entity, driven by interfacial tension and...
Static multiple light scattering
Static multiple light scattering (SMLS) is an optical technique that characterizes concentrated liquid dispersions in their native state, monitoring stability a...
Metalworking fluids
Metalworking fluids are liquids or gases used in machining to cool, lubricate, and remove chips, extending tool life and improving workpiece quality.
Bioprocess
A bioprocess uses controlled cells, microorganisms or enzymes to produce, transform or purify substances of interest.
Bioreactor
A bioreactor maintains controlled conditions for cultivating cells or microorganisms and performing biological processes.
Dissolved oxygen
Dissolved oxygen is the amount of molecular oxygen present in a liquid and available to cells, microorganisms and chemical reactions.
Bioprocess scale-up
Bioprocess scale-up transfers a biological process between scales while preserving performance, control and product quality.
Microtiter plates
Microtiter plates are multiwell laboratory vessels used to prepare, cultivate and analyze many samples in parallel.
ANSI/SLAS
ANSI/SLAS is a family of standards for microplate dimensions and well positions used in laboratories and automated systems.
cell viability
Cell viability is the measure of the proportion of live, healthy cells in a sample, essential in cell culture and research.
Trypan blue exclusion
Trypan blue exclusion is a method that distinguishes viable and nonviable cells based on cell membrane integrity.
Extracellular Vesicles
Extracellular vesicles are cell-released nanoparticles that carry proteins, lipids and genetic material, enabling cell-to-cell communication.
Differential Ultracentrifugation
A technique that separates sample particles through successive centrifugation steps at increasing speeds based on size, mass, and density.
Nanoparticle Tracking Analysis
A technique that tracks individual nanoparticles in suspension to determine particle size distribution and concentration.
Endosomal Compartment of Cells
A system of organelles that receives, sorts, and directs internalized cellular cargo toward recycling, degradation, or other destinations.
Exosomes
Exosomes are small extracellular vesicles released by cells that transport biomolecules and participate in intercellular communication.
Extracellular vesicle isolation
Extracellular vesicle isolation separates and enriches EVs from biological fluids or culture media for subsequent analysis and characterization.
Extracellular vesicle characterization
Extracellular vesicle characterization uses complementary techniques to evaluate EV size, concentration, markers and physicochemical properties.
Zeta potential
Zeta potential is an electrokinetic parameter related to particle surface charge and the stability behavior of colloidal dispersions.
Exosome biomarkers
Exosome biomarkers are vesicle-associated molecules used to investigate EV origin, composition and potential biological functions.
Exosome purification
Exosome purification reduces contaminants and enriches vesicles of interest for subsequent physical, molecular and functional analysis.
Dissolved Oxygen (DO)
Dissolved Oxygen (DO) is the concentration of molecular oxygen present in a liquid and available for biological or chemical processes.
Oxygen Transfer Rate (OTR)
Oxygen Transfer Rate (OTR) is the rate at which oxygen moves from the gas phase into the liquid phase of a culture or process system.
Fed-Batch Cultivation
Fed-batch cultivation is a process in which nutrients are added during culture without continuous removal of the culture medium.
Reactive Oxygen Species (ROS)
Reactive Oxygen Species (ROS) are oxygen-derived molecules and radicals that participate in cellular oxidation and redox signaling.
Specific Growth Rate (μ)
Specific growth rate (μ) describes the rate of biomass increase relative to the amount of biomass already present in a culture.
Light Obscuration
Light Obscuration is an optical technique that counts and sizes particles in liquids by detecting the loss of light as particles cross a sensor.
Japanese Pharmacopoeia (JP)
The Japanese Pharmacopoeia (JP) is Japan's official compendium establishing quality standards, tests and specifications for medicines.
United States Pharmacopeia (USP)
The United States Pharmacopeia (USP) is a compendium of public quality standards for medicines, substances and analytical procedures in the U.S.
Liposomal formulations
Liposomal formulations use lipid vesicles to incorporate, carry or release active substances within a structured lipid-based delivery system.
Adsorption isotherm
An adsorption isotherm is the curve relating the amount of adsorbate taken up by a solid to the pressure or concentration of the fluid phase at constant tempera...
MOF (Metal-Organic Framework)
A MOF is a class of porous crystalline material built from metal ions or clusters linked by organic ligands, exhibiting permanent porosity.
Carbon capture
Carbon capture refers to the processes used to separate and concentrate CO₂ from gas streams or ambient air for subsequent storage or utilization.
Electrokinetic mobility window
Range of electrophoretic mobilities where the analyzer produces linear, high-resolution measurements under controlled electric field, pH, and ionic strength con...
Bioanalytical method bridging
Process aligning legacy and new bioanalytical assays to demonstrate continuity of precision, accuracy, and stability for regulatory submissions, often required...
Nanoparticle dispersity index
Metric describing distribution breadth of nanoparticle sizes within a sample, guiding formulation adjustments for uniform delivery, stability, and safety across...
Water vapor sorption
Process by which a material adsorbs or absorbs water vapor from the environment, affecting stability, storage, and performance.
Desorption
Release of previously sorbed (adsorbed or absorbed) molecules from a surface or solid matrix.
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