Particle Size Analyzer - LS 13 320 XR

The LS 13 320 XR Particle Size Analyzer offers a wide measurement range, precise sub-μm particle detection, intuitive software, and compliance with GMP and 21 CFR Part 11 .

This instrument from Beckman Coulter is designed to provide high-resolution particle size distribution data while strictly adhering to the standards of ISO 13320 from the International Organization for Standardization , helping to identify small differences that can have a major impact on your analyses.

Key Features of the LS 13 320 XR Particle Size Analyzer

Wide Measurement Range Compliant with ISO 13320

The LS 13 320 XR Particle Size Analyzer offers a direct measurement range from 10 nm to 3,500 µm, allowing for accurate detection of multiple particle sizes in a single sample according to ISO 13320 standard specifications. This is made possible by advanced Laser Diffraction technology combined with Polarization Intensity Differential Scattering ( PIDS ), which enables measurement and acquisition of real data with high resolution down to 10 nm. The use of 132 detectors ensures even higher resolution and more accurate results, meeting the rigorous requirements for laser diffraction analysis established by the ISO 13320 standard.

Intuitive and User-Friendly Software

The ADAPT software simplifies operation of the particle size analyzer for both experts and novice users. With pre-configured methods compliant with ISO 13320 protocols, you can obtain results with just three clicks. The software also includes automatic pass/fail checks, one-click historical data overlay, and intuitive diagnostics that keep you informed during sampling. 

Additionally, ADAPT enables the creation of streamlined methods for standardized measurements and is compliant with 21 CFR Part 11, offering a customizable security system with four security levels, including secure user login, user-level permissions, audit trail, error log files, and administrative configuration tools.

Direct Detection of 10 nm Particles with PIDS Technology

With three wavelengths of light (450, 600, and 900 nm) irradiating samples with vertically and horizontally polarized light, the analyzer measures the scattered light from samples across an angular range, following the fundamental principles of ISO 13320 for particle size analysis by laser diffraction. The differences between horizontally and vertically irradiated light for each wavelength result in high-resolution particle size distribution data. This enhanced PIDS technology allows for more accurate raw data detection and greater sensitivity of the polarized scattered light detector in the vertical and horizontal positions, essential for sub-μm particle size analysis.

Validation and Compliance with Good Manufacturing Practices (GMP)

The LS 13 320 XR facilitates the implementation of Good Manufacturing Practices (GMP) with specific tools for Installation Qualification (IQ) and Operational Qualification (OQ). Compliance with 21 CFR Part 11 ensures data integrity and regulatory compliance, essential for regulated environments.

Compliance with ISO 13320 - International Standard for Particle Analysis

What is ISO 13320

ISO 13320 is the international standard that establishes standardized methods for particle size analysis by laser diffraction . This standard defines procedures, calibration requirements, measurement methods, and validation criteria to ensure accurate and reproducible results in determining particle size distribution.

How the LS 13 320 XR Meets ISO 13320 Requirements

The LS 13 320 XR was developed in full compliance with the requirements of ISO 13320 , offering:

• Validated laser diffraction methodology according to the standard's specifications
• Calibration protocols that strictly follow ISO 13320 standards
• Metrological traceability of measurement results
• Instrument performance verification procedures
• Complete technical documentation as required by the standard

Advantages of ISO 13320 Compliance

Compliance with ISO 13320 ensures that results obtained with the LS 13 320 XR are:

• Internationally recognized
• Comparable between different laboratories
• Valid for regulatory submissions
• Suitable for quality control in industrial processes

Benefits for Your Laboratory with the Particle Size Analyzer

Fast and Reliable Quality Control

The LS 13 320 XR Particle Size Analyzer automatically highlights pass/fail results following criteria based on ISO 13320 , streamlining quality control and enabling quick, informed decisions. The new control standardization ensures that instrument and module performance is properly verified.

Improved Workflow Efficiency

With features that simplify operation and standardized methods according to ISO 13320 , the LS 13 320 XR Particle Size Analyzer helps optimize your laboratory's efficiency. Whether for accurate detection of multiple particle sizes or for simplified method creation, this particle size analyzer is designed to significantly improve your workflows.

Explore the LS 13 320 XR Particle Size Analyzer Models

For more information about available models and how the LS 13 320 XR Particle Size Analyzer can benefit your particle analysis operations with full compliance to ISO 13320 , access our resources and tools or contact our technical support team at Dafratec, Beckman Coulter representative.

Frequently Asked Questions - LS 13 320 XR and ISO 13320

Is the LS 13 320 XR certified according to ISO 13320?

Yes, the LS 13 320 XR fully meets the requirements of ISO 13320 for particle size analysis by laser diffraction, ensuring standardized and internationally recognized results.

What is the measurement range of the equipment according to ISO 13320?

The equipment offers direct measurement from 10 nm to 3,500 µm , exceeding the minimum requirements of ISO 13320 and enabling analysis of a wide range of materials in compliance with the standard.

Does the ADAPT software follow ISO 13320 protocols?

Yes, the ADAPT software includes pre-configured methods that follow the protocols established by ISO 13320 , in addition to offering complete data traceability as required by the standard.

How does the LS 13 320 XR ensure the repeatability required by ISO 13320?

Through advanced PIDS technology and 132 high-precision detectors, the equipment ensures result repeatability and reproducibility according to ISO 13320 specifications.

Is specific ISO 13320 training required to operate the equipment?

The intuitive ADAPT software simplifies operation by automatically following ISO 13320 protocols, allowing users with different experience levels to obtain valid and reliable results.

Does the equipment generate reports compliant with ISO 13320?

Yes, the LS 13 320 XR generates complete technical reports that meet the documentation requirements of ISO 13320 , including all parameters and measurement conditions required by the standard.

The LS 13 320 XR Particle Size Analyzer is the ideal solution for those seeking precision, reliability, and efficiency in particle size analyses with full adherence to the international standards of ISO 13320 . Don't miss the opportunity to enhance your analyses with the cutting-edge technology of this particle size analyzer offered by Dafratec.